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KMID : 0191120170320061038
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Journal of Korean Medical Science
2017 Volume.32 No. 6 p.1038 ~ p.1041
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Clinical and Genetic Features of Coxiella burnetii in a Patient with an Acute Febrile Illness in Korea
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Lee Seung-Hun
Heo Jung-Yeon
Lee Hae-Kyung
Lee Yeong-Seon
Jeong Hye-Won
Hwang Se-Hwan
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Abstract
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Although Q fever is an important zoonotic infection with a worldwide distribution, no human isolates of Coxiella burnetii have been identified in Korea. For the first time, we identified the nucleotide sequence of C. burnetii from a 32-year-old man with an acute febrile illness in Korea. Diagnosis of acute Q fever was confirmed by seroconversion using indirect immunofluorescence antibody assays. Phylogenetic analysis demonstrated high sequence similarity (99.6%?100%) with C. burnetii 16S rRNA sequences identified from the reservoir. These results are the first genetic analysis of C. burnetii in a human case of Q fever in Korea.
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KEYWORD
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16s rRNA, Coxiella burnetii, Korea, Q Fever
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